Animal units

The main task for UCCB is to house and breed laboratory animals according to the needs of the scientists working at Umea University.

Only healthy animals can meet the requirements of research. Therefore, UCCB make sure that the housing and handling of laboratory animals is carried out under high hygienic levels and according to the natural needs of each species.

The main species (>90 percent) are mice, rats and zebrafish.

Handling routines and the design of the different animal units in combination with the choice of cage should provide the best conditions for the studies.

UCCB reserve the right to decide where animals should be placed and if and with whom the different research groups should share animal rooms with.

Descriptions of the different animal units

Conventional animal units A and B

 

Corridor animal unit

Photo: UCCB

A and B units are intended for housing/husbandry as well as experimental use of mice and rats.

The open units are designed for a high degree of disease control. The majority of rodents are kept in open-top cage system but immmunodefective straines are always housed in IVC. Read more about the different cage systems.

Researchers and their personnel have access to the open animal units after proper training and introduction of the facilities rules and routines.

Umeå Zebrafish Facility (UZF)

Umeå Zebrafish Facility

Photo: UCCB

Umeå Zebrafish Facility (UZF) is designed for housing and breeding of zebrafish. It is located within the B unit in one of the conventional animal units.

Researchers and their personnel get access to UZF after proper training and introduction of the facilities rules and routines.

More information at UZF.

Barrier unit

Intended for housing/husbandry of breeding rodents. Only documented clean purchased strains are allowed to be transferred and used inside the barrier unit.

If you need to breed on strains kept in the open units, an embryo transfer is necessary. To avoid that infectious agents are transferred between animals, no mature or postnatal strains are allowed to be transferred into the barrier.

All animals are kept in IVC systems.

The entrance to the Barrier unit is preceded by an second air shower. Note, that the work at the barrier is undertaken as a first duty in the mornings. Taken together these procedures should reduce the risk that microorganisms are transferred from the staff to the animal colony.

Researchers and their personnel are not allowed to enter into the Barrier.

Infection unit

Intended for infection studies on mouse and rat, involving microorganisms and/or cell lines classified up to BSL 2, studies that involve harmfull drugs or chemicals, or the IVIS.

All animals are kept in IVC systems.

Remember that it is only UCCB staff that take care of transfer of animals into the Infection unit.

To avoid that the animal colony get contaminating infections all passage into the unit is preceded with a change of work clothes and entrance is through an air-shower. Since we also want to avoid the spread of infections from the Infection unit, the passage out from the infection unit is through the air-showered followed with a change of work clothes.

Researchers and their personnel have access to the Infection unit after proper training and introduction of the facilities rules and routines.

Remember to plan your work carefully since you are not allowed to work at the Infection unit and then continue the work at the open animal units on the same day.

Quarantine unit

Placed outside the enclosing of UCCB. The unit is used for quarantine and observation of purchased or imported animals that should be transferred into UCCB (after health check) or for animals that participate in ongoing experiments when instruments outside the UCCB is used.

All animals are kept in IVC systems.

Researchers that perform studies on laboratory animals while using instruments outside UCCB get access to the quarantine.

Note due to the contamination risk, you are not allowed on the same day to start to work with quarantined animals and then continue to work in other animal units within UCCB.

Large animal unit

Placed outside the enclosing of UCCB and consists of short time housing and husbandry for pig and rabbit.

Researchers and their personnel have access to the Large animal unit after proper training and introduction of the facilities rules and routines.

Cathrine Persson
11/17/2022