Two Seahorses have moved into the 6M-building

    12 September 2016

    Umeå University recently acquired a pair of Seahorses, instruments that enable metabolism to be measured in living cells, in real time. Acquired through generous support from Kempestiftelserna and VLL, the Seahorse instruments are accessible for all interested research groups. A training course is being offered September 14-15.

    "The Seahorse platform offers sophisticated instrumentation to analyze cell metabolism; a rapidly growing area in biomedical research" says Jonathan Gilthorpe, Group Leader at the Department of Pharmacology and Clinical Neuroscience. "Having access to this technology should benefit a wide variety of research projects."

     

    Photo: Jonathan Gilthorpe

    The Seahorse platform includes two instruments. The XFe96 Bioanalyser enables analysis of a large number of samples in 96-well plates and the XFp Bioanalyser is used for comparisons of a pair of samples.

    Changes in cellular metabolism are important for normal cellular and physiological processes but also in many diseases where metabolic dysfunction or metabolic reprogramming is known to occur. Metabolism is powered by two main energy producing pathways − mitochondrial respiration and glycolysis. The Seahorse technology quantifies metabolism through these pathways, providing insight into mitochondrial function and glycolytic activity in live cells in real time.

    Access and training

    The platform is accessible to all interested research groups and will be available through a 'user club'. An introductory training course is being offered September 14-15 for interested parties. For more information, please contact Jonathan Gilthorpe, Department of Pharmacology and Clinical Neuroscience (jonathan.gilthorpe@umu.se; 090-785-4439).

    More information about the Seahorse platform:

    http://www.agilent.com/en-us/promotions/xftechnologyoverview

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